Importance of tyrosine phosphorylation for transmembrane signaling in plants

Reversible protein phosphorylation is a widespread post-translational modification fundamental for signaling across all domains of life. Tyrosine (Tyr) has recently emerged as being important plant receptor kinase (RK)-mediated signaling, particularly during immunity. How Tyr regulates RK function however largely unknown. Notably, the expansion phosphatase and SH2 domain-containing families, which are core regulatory phospho-Tyr (pTyr) networks in choanozoans, did not occur plants. Here, we summarize current understanding focusing on critical role pTyr site (‘VIa-Tyr’) conserved several RKs. Furthermore, discuss possibility metazoan-like modules plants based atypical components with convergent biochemical functions.